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BMP2 — WISP1

Text-mined interactions from Literome

Parisi et al., Bone 2006 : Nuclear run-on assays revealed that TGF beta, BMP-2 and cortisol enhanced CYR61 and CTGF transcription, TGF beta and BMP-2 induced and cortisol suppressed WISP 1 , and TGF beta induced WISP 2 transcription
Ono et al., J Bone Miner Res 2011 : WISP-1/CCN4 regulates osteogenesis by enhancing BMP-2 activity ... Immunoprecipitation ( IP ) and Western blot analysis showed that WISP-1 bound directly to BMP-2 and showed that WISP-1 increased BMP-2 binding to hBMSCs in a dose dependent fashion ... Antibody blocking experiments showed that the BMP-2 binding to BMSCs that was enhanced by WISP-1 was completely neutralized by treatment with anti-integrin a ( 5 ) ß ( 1 ) antibody