Gene interactions and pathways from curated databases and text-mining

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CSF2 — IL23A

Text-mined interactions from Literome

Sonderegger et al., J Exp Med 2008 (Autoimmune Diseases...) : We found that innate GM-CSF was critical for IL-6 and IL-23 responses by dendritic cells and generation of pathological Th17 cells in vivo
van de Wetering et al., PloS one 2009 (Salmonella Infections) : In addition, IL-23 together with IL-18 or IL-1beta led to the production of GM-CSF in CD56 ( + ) cells ... Both IFN-gamma and GM-CSF enhanced IL-23 production by monocytes in response to TLR agonists, as well as induced IL-12 production
El-Behi et al., Nat Immunol 2011 (Encephalomyelitis, Autoimmune, Experimental) : Here we found that IL-23 induced production of the cytokine granulocyte-macrophage colony stimulating factor ( GM-CSF ) in T ( H ) 17 cells and that GM-CSF had an essential role in their encephalitogenicity ... IL-23 induced a positive feedback loop whereby GM-CSF secreted by T ( H ) 17 cells stimulated the production of IL-23 by antigen presenting cells