Gene interactions and pathways from curated databases and text-mining

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ICAM1 — IL17D

Text-mined interactions from Literome

Owaki et al., J Immunol 2005 : IL-27 rapidly up-regulated the expression of ICAM-1 on naive CD4+ T cells, but not on APCs, and blocking Abs against ICAM-1 and LFA-1 inhibited the IL-27 induced Th1 differentiation ... Although IL-27 augmented T-bet expression in naive CD4+ T cells as previously reported, T-bet was not necessary for the IL-27 induced rapid up-regulation of ICAM-1 expression and Th1 differentiation
Larousserie et al., J Immunol 2006 : In anti-Ig stimulated naive or memory B cells, IL-27 also induced CD54 , CD86, and CD95 surface expression
Feng et al., Biochem Biophys Res Commun 2008 : In addition, IL-27 enhances expression of costimulatory molecules CD80 and CD86 and adhesion molecule CD54
Shimozato et al., Immunology 2009 (Neoplasms) : The secreted mp28 prevented the IL-27 mediated signal transduction and activator of transcription 1 phosphorylation and subsequently inhibited the IL-27 mediated intercellular adhesion molecule-1 induction and interferon-gamma production in CD4 ( + ) T cells