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ERVK-6 — TNF
Text-mined interactions from Literome
Sakamoto et al., Immunopharmacology 1999
:
On the other hand, the 45 kDa
proteinase did not
stimulate the production of PGE2, IL-1beta, and
TNF-alpha from the macrophages
Majka et al., Invest Ophthalmol Vis Sci 2002
(Retinal Neovascularization) :
The
role of
TNFalpha in stimulating retinal microvascular endothelial cell ( RMVEC )
proteinase production was evaluated using isolated murine RMVECs grown in normoxic or hypoxic conditions
Smith et al., Clin Immunol Immunopathol 1992
:
Neutral
proteinase and PGE2 production by BNC was also
induced by
TNF alpha ( 0.2-200 ng/ml ) in a time dependent ( 0-72 hr ) manner
Zhang et al., Cell Physiol Biochem 2010
:
However, little is known of the
effects of
TNF on cytokine secretion and
protease activated receptor (PAR) expression in mast cells
Okada et al., Biochem Biophys Res Commun 1990
(Fibrosarcoma...) :
Among the cytokines and growth factors examined, only human recombinant
tumor necrosis factor alpha (TNF alpha) induced and
stimulated the
proteinase with concomitant increase in TIMP expression, but matrix metalloproteinase 2 ( 72-kDa gelatinase/type IV collagenase ) expression was unchanged
Jeong et al., Immunology 1997
:
Serine
proteinase inhibitors such as N-tosyl-L-phenylalanine chloromethyl ketone ( TPCK ) and N alpha-p-tosyl-L-lysine chloromethyl ketone ( TLCK ) were shown to
inhibit production of
tumour necrosis factor-alpha (TNF-alpha) in lipopolysaccharide (LPS) activated RAW 264.7 macrophages
Curtis et al., Am J Physiol 1998
:
Because
TNF-alpha can
induce proteinase expression in endothelial cells, we determined whether proteinases cause both the alteration of the Fn matrix and the permeability increase as is often speculated
Reno et al., Biochem Biophys Res Commun 1998
:
In addition, mRNA levels for IL-1,
TNF , COX-2, and iNOS, potential
regulators of
proteinase/inhibitor expression, have been assessed