Gene interactions and pathways from curated databases and text-mining

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ERVK-6 — TNF

Text-mined interactions from Literome

Sakamoto et al., Immunopharmacology 1999 : On the other hand, the 45 kDa proteinase did not stimulate the production of PGE2, IL-1beta, and TNF-alpha from the macrophages
Majka et al., Invest Ophthalmol Vis Sci 2002 (Retinal Neovascularization) : The role of TNFalpha in stimulating retinal microvascular endothelial cell ( RMVEC ) proteinase production was evaluated using isolated murine RMVECs grown in normoxic or hypoxic conditions
Smith et al., Clin Immunol Immunopathol 1992 : Neutral proteinase and PGE2 production by BNC was also induced by TNF alpha ( 0.2-200 ng/ml ) in a time dependent ( 0-72 hr ) manner
Zhang et al., Cell Physiol Biochem 2010 : However, little is known of the effects of TNF on cytokine secretion and protease activated receptor (PAR) expression in mast cells
Okada et al., Biochem Biophys Res Commun 1990 (Fibrosarcoma...) : Among the cytokines and growth factors examined, only human recombinant tumor necrosis factor alpha (TNF alpha) induced and stimulated the proteinase with concomitant increase in TIMP expression, but matrix metalloproteinase 2 ( 72-kDa gelatinase/type IV collagenase ) expression was unchanged
Jeong et al., Immunology 1997 : Serine proteinase inhibitors such as N-tosyl-L-phenylalanine chloromethyl ketone ( TPCK ) and N alpha-p-tosyl-L-lysine chloromethyl ketone ( TLCK ) were shown to inhibit production of tumour necrosis factor-alpha (TNF-alpha) in lipopolysaccharide (LPS) activated RAW 264.7 macrophages
Curtis et al., Am J Physiol 1998 : Because TNF-alpha can induce proteinase expression in endothelial cells, we determined whether proteinases cause both the alteration of the Fn matrix and the permeability increase as is often speculated
Reno et al., Biochem Biophys Res Commun 1998 : In addition, mRNA levels for IL-1, TNF , COX-2, and iNOS, potential regulators of proteinase/inhibitor expression, have been assessed