Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
FAS
→
PAWR
(increases, PAWR Activity)
Chakraborty et al., Cancer Res 2001* Evidence: Par-4 induced apoptosis of selective prostate cancer cells PC-3, DU-145, and TSU-Pr and caused tumor regression by inhibition of NF-kappaB activity and cell membrane trafficking of Fas and FasL that leads to the activation of the Fas-Fas-associated death domain-caspase-8 pro-death pathway.