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PTGS2 — TGFA

Text-mined interactions from Literome

Matsuura et al., J Biol Chem 1999 (Carcinoma, Squamous Cell) : Regulation of cyclooxygenase-2 by interferon gamma and transforming growth factor alpha in normal human epidermal keratinocytes and squamous carcinoma cells
Sawaoka et al., Prostaglandins Leukot Essent Fatty Acids 1999 : The transforming growth factor alpha induced expression of cyclooxygenase-2 is followed by cell proliferation and development of tubular morphology of RGM1 gastric epithelial cells
Grossman et al., Carcinogenesis 2000 (Gallbladder Neoplasms) : Employing a human gall bladder cancer cell line, mitogenesis, apoptosis and prostaglandin E ( 2 ) ( PGE ( 2 ) ) formation were evaluated in response to serum and hepatocyte growth factor and transforming growth factor alpha stimulation in the presence and absence of specific COX-1 and -2 inhibitors
Al-Salihi et al., Cell Signal 2007 : Both transforming growth factor-alpha and amphiregulin were released in response to over-expression of cyclooxygenase-2 , but betacellulin and heparin binding EGF-like growth factor were not
Angelucci et al., Endocr Relat Cancer 2008 (Breast Neoplasms...) : While 5-LOX controls cell survival through the regulation of the Bcl-2/Bax ratio, COX-2 activity stimulates the release of transforming growth factor-alpha ( TGF-alpha ) and pro-inflammatory cytokines