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BCL2 — HPR

Text-mined interactions from Literome

Simile et al., Carcinogenesis 2005 (Cell Transformation, Neoplastic...) : SL-HPR prevented these changes and induced a decrease in expression of iNos, c-myc, cyclin D1 and Vegf-A genes, that were over expressed in preneoplastic liver and nodules, and a decrease in Bcl-2/Bax, Bcl-2/Bad and Bcl-xL/Bax mRNA ratios with respect to the lesions of control rats
Wang et al., Cancer Lett 1996 (Breast Neoplasms) : We found that : ( 1 ) 4-HPR treatment resulted in decreased Bcl-2 mRNA but not Bax mRNA levels ; ( 2 ) the effect of 4-HPR on Bcl-2 mRNA level was different from other retinoids ; ( 3 ) 4-HPR treatment induced apoptosis in both estrogen receptor positive and -negative cells