◀ Back to IRF7

IRF7 — MYD88

Pathways - manually collected, often from reviews:

• Reactome Reaction: IRF7 → MYD88 (indirect_complex) Kawai et al., Nat Immunol 2004, Honda et al., Proc Natl Acad Sci U S A 2004*, Uematsu et al., J Exp Med 2005, Ning et al., Mol Cell Biol 2008
• Reactome Reaction: IRF7 → MYD88 (reaction) Marié et al., Mol Cell Biol 2000*, Kawai et al., Nat Immunol 2004, Honda et al., Proc Natl Acad Sci U S A 2004*, Uematsu et al., J Exp Med 2005, Ning et al., Mol Cell Biol 2008
• WikiPathways Structural Pathway of Interleukin 1 (IL-1): MYD88 → IRF7 (activation)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Bind Interaction: MYD88 — IRF7 Kawai et al., Nat Immunol 2004
• IRef Bind_translation Interaction: MYD88 — IRF7 (two hybrid) Kawai et al., Nat Immunol 2004
• IRef Bind_translation Interaction: MYD88 — IRF7 (fluorescent resonance energy transfer) Kawai et al., Nat Immunol 2004
• IRef Bind_translation Interaction: MYD88 — IRF7 (coimmunoprecipitation) Kawai et al., Nat Immunol 2004
• IRef Biogrid Interaction: MYD88 — IRF7 (direct interaction, fluorescent resonance energy transfer) Kawai et al., Nat Immunol 2004
• IRef Biogrid Interaction: MYD88 — IRF7 (physical association, affinity chromatography technology) Zhao et al., J Biol Chem 2006*
• IRef Biogrid Interaction: MYD88 — IRF7 (direct interaction, two hybrid) Kawai et al., Nat Immunol 2004
• IRef Biogrid Interaction: MYD88 — IRF7 (physical association, affinity chromatography technology) Kawai et al., Nat Immunol 2004
• IRef Hprd Interaction: MYD88 — IRF7 (in vivo) Kawai et al., Nat Immunol 2004
• IRef Hprd Interaction: MYD88 — IRF7 (two hybrid) Kawai et al., Nat Immunol 2004

Text-mined interactions from Literome

Schoenemeyer et al., J Biol Chem 2005 : We also demonstrate that MyD88 , interleukin 1 receptor associated kinase 1, and tumor necrosis factor receptor associated factor 6 are required for the activation of IRF5 and IRF7 in the TLR7 signaling pathway
Honda et al., Nature 2005 : It is absolutely dependent on the transcription factor IRF-7 , which interacts with and is activated by the adaptor MyD88