Ardans et al., J Leukoc Biol 2002
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This conclusion was supported further by ox-LDL mediated increases in PGE2 and cyclooxygenase-2 (COX-2) production
Kanayama et al., J Biol Chem 2007
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Moreover, we characterized the cellular events triggered by the combined stimulus of HNE and oxidized LDL and established that COX-2 induction is regulated by two sets of signaling mechanisms, one for the up-regulation of the scavenger receptor CD36 by HNE and one for the CD36 mediated COX induction by oxidized LDL