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GAST — NFKB1

Text-mined interactions from Literome

Medina et al., Microb Pathog 2002 : The objective of this study was to investigate the ability of group A streptococci (GAS) to stimulate the nuclear translocation of NF-kappaB in cultured human epithelial ( HEp-2 ) cells
Ogasa et al., Gut 2003 : Gastrin activates nuclear factor kappaB (NFkappaB) through a protein kinase C dependent pathway involving NFkappaB inducing kinase, inhibitor kappaB (IkappaB) kinase, and tumour necrosis factor receptor associated factor 6 ( TRAF6 ) in MKN-28 cells transfected with gastrin receptor ... Gastrin induced degradation of IkappaB-alpha and activation of NFkappaB , which was abolished by the selective gastrin receptor antagonist L-740,093 and the general PKC inhibitor GF109203X ... Gastrin induced phosphorylation of PKC-delta, and its inhibitor rottlerin partially suppressed NFkappaB activation ... Gastrin activates NFkappaB via a PKC dependent pathway which involves IkappaB kinase, NFkappaB inducing kinase, and TRAF6
Agresti et al., Eur J Neurosci 1998 : The existence of a synergism between IFN-gamma and TNF-alpha in stimulating IRF-1 expression at the transcriptional level was supported by IRF-1 promoter analysis : IFN-gamma directly induced the binding of STAT-1 homodimers to the GAS element, while NF-kappaB binding to the kappaB sequence was activated by TNF-alpha only after IFN-gamma treatment