UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

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SMAD3 — TP53

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

IRef Biogrid Interaction: SMAD3 — TP53 (physical association, affinity chromatography technology) Lu et al., J Biol Chem 2013 *
IRef Biogrid Interaction: SMAD3 — TP53 (direct interaction, pull down) Cordenonsi et al., Cell 2003 *
IRef Biogrid Interaction: SMAD3 — TP53 (physical association, affinity chromatography technology) Cordenonsi et al., Cell 2003 *
IRef Hprd Interaction: TP53 — SMAD3 (in vitro) Cordenonsi et al., Cell 2003 *
IRef Hprd Interaction: TP53 — SMAD3 (in vivo) Cordenonsi et al., Cell 2003 *

Text-mined interactions from Literome

Wang et al., J Biol Chem 2007 : Expression of ectopic p53 , however, restored ligand induced association of Smad2/3 with a transfected Maspin promoter
Wiegman et al., Radiother Oncol 2007 : However, as shown by the use of a specific inhibitor TGFbeta-1-receptor I-Smad signalling was not involved in this fast activation of ATM and p53