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CD2 — CD4

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Hprd Interaction: CD2 — CD4 (in vitro) Dianzani et al., Eur J Immunol 1995*
• IRef Ophid Interaction: CD2 — CD4 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005
• IRef Ophid Interaction: CD2 — CD4 (aggregation, confirmational text mining) Dianzani et al., Eur J Immunol 1995*

Text-mined interactions from Literome

Dang et al., J Immunol 1990 : These findings thus suggest that the CD26 Ag is involved in CD3 and CD2 induced human CD4+ T cell activation
Kashiwakura et al., Immunology 2013 : CD2 mediated regulation of peripheral CD4 ( + ) CD25 ( + ) regulatory T-cell apoptosis accompanied by down-regulation of Bim
Inverardi et al., J Immunol 1988 : We have evaluated the effects of anti-CD2 and anti-CD3 mAb and the calcium ionophore A23187 on CD4+ and CD8+ allospecific cytolytic clones
Carvalho et al., Immunol Lett 1988 : The following markers were examined : E-rosette formation, CD2, CD3, CD4 , CD8, CD1, CD22, CD10 and HLA-DR. Pretreatment of peripheral blood lymphocytes ( PBL ) with Fe-citrate at concentrations ranging from 10 ( -2 ) M to 10 ( -5 ) M resulted in the exclusive inhibition of E-rosette formation and CD2 expression
Van Gool et al., Scand J Immunol 1995 : We conclude that CD28 ligation with the natural ligand B7-1 provides a strong accessory signal for CD4 and CD8 cell activation through CD2
Eljaafari et al., J Immunol 1994 : We show that T cell activation of human CD4+ cloned T cells through the CD2 molecule can induce either autocrine proliferation or cytolysis, depending on the pair of anti-CD2 mAbs used for stimulation, that is, D66/T11 ( 1 ) or GT2/T11 ( 1 ), respectively