Gene interactions and pathways from curated databases and text-mining

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ADAM17 — IL6

Text-mined interactions from Literome

Dreymueller et al., EMBO Mol Med 2012 (Inflammation...) : Induced vascular permeability, oedema formation, release of TNF-a and IL-6 and pulmonary leukocyte recruitment were all markedly reduced by GW280264X or endothelial adam17-knockout
Yu et al., Cancer Res 2013 : Either miR-145 suppression or ADAM17 overexpression in non-TICs/ALDH1 ( - ) CD44 ( - ) -HNC cells increased expression and secretion of interleukin (IL)-6 and soluble-IL-6 receptor ( sIL-6R )