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CDKN1B — TGFB2

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: CDKN1B → TGFB2 (increases) Kim et al., Molecular vision 2001*
  Evidence: TGF-beta2 markedly downregulated Cdk4 synthesis and slightly upregulated p27 synthesis
• OpenBEL Selventa BEL large corpus: CDKN1B → TGFB2 (decreases) Kim et al., Molecular vision 2001*
  Evidence: TGF-beta2 inhibited phosphorylation of p27 in actively cycling cells

Text-mined interactions from Literome

Joyce et al., Invest Ophthalmol Vis Sci 2002 : Studies were then extended to cultured cells to more directly compare the effects of TGF-beta2 and cell-cell contact on the relative protein and mRNA expression of the CKIs, p27kip1 , and p15INK4b
Donovan et al., J Biol Chem 2002 : Non-malignant and tumor derived cells differ in their requirement for p27Kip1 in transforming growth factor-beta mediated G1 arrest
Ponce-Castañeda et al., Cancer Res 1995 (Neoplasms) : These results argue that the often observed loss of antimitogenic transforming growth factor beta responsiveness in human cancer cells is not due to structural defects in p27Kip1
Wolf et al., Am J Physiol 1997 (Hypertrophy) : High glucose stimulated expression of p27Kip1 involved activation of protein kinase C and was partly dependent on induction of transforming growth factor-beta ( TGF-beta )