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FSCN1 — IL2
Text-mined interactions from Literome
Froussard et al., Mol Immunol 1991
:
These data confirm that
IL-2 upregulates
p55 IL-2 receptor gene expression while IL-4, which also activates T cells, does not lead to specific induction of this gene
Tamori et al., Nihon Ketsueki Gakkai Zasshi 1989
:
1 alpha, 25 ( OH ) 2D3 enhanced the expression of IL-2 receptor (
p55 , Tac peptide ) in phytohemagglutinin ( PHA ) -stimulated ( 3 days ) human peripheral blood mononuclear cells ( PBM ) only in the
presence of
IL-2 without affecting the proliferation of the cells
Xu et al., Int Arch Allergy Immunol 1993
:
Given that
IL-2 upregulates
p55 expression and is involved in the formation of HA-IL-2R, our results suggest that defective IL-2 expression is the primary lesion in age related T cell senescence
Arbour et al., Bone Marrow Transplant 1996
:
In addition,
induction of
p55 by
IL-2 was abrogated in autologous PB NK cells