Torigoe et al., Leukemia 1992
:
This finding that p53/56-LYN can be regulated by both IL-2 in B-lineage cells and IL-3 in myeloid committed cells demonstrates that the same SRC-family PTK can participate in signal transduction events mediated via two independent receptor systems
Yamamoto et al., Princess Takamatsu symposia 1991
:
Under the same conditions, normal Lck and Lyn could not stimulate IL-2 promoter
Shuh et al., J Virol 2011
(Cell Transformation, Viral) :
Lyn coimmunoprecipitates with the interleukin-2 beta receptor ( IL-2Rß ) and JAK3 proteins ; however, the association of Lyn with the IL-2Rß and Lyn kinase activity was independent of IL-2 stimulation
Kobayashi et al., Proc Natl Acad Sci U S A 1993
:
We observed that in this cell line, IL-2 induces activation of at least two src-PTKs, p59fyn ( fyn ) and p53/56lyn ( lyn )