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IL2 — TEC

Text-mined interactions from Literome

Yang et al., J Immunol 2001 : Using several PH domain mutants overexpressed in Jurkat T cells, we show that the Tec PH domain is required for Tec mediated IL-2 gene induction and TCR mediated Tec tyrosine phosphorylation ... Wortmannin, a phosphatidylinositol 3-kinase inhibitor, abolishes Tec mediated IL-2 gene induction and Tec tyrosine phosphorylation, and partially suppresses Tec colocalization with the activated TCR
Zemans et al., Cell Immunol 2009 : Furthermore, LPS induced actin polymerization as well as MCP-1, tumor necrosis factor-alpha, interleukin-6 , and interleukin-1beta expression are dependent on Tec kinase activity