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IL2 — TNFSF10

Text-mined interactions from Literome

Johnsen et al., Cytokine 1999 : NK cells were shown to express surface Apo-2L in response to interleukin 2 (IL-2) activation, and this response was restricted to the CD3 ( - ) population of the NK cells
Musgrave et al., Exp Cell Res 1999 : However, TRAIL mRNA expression was not induced by IL-2 , suggesting that TRAIL gene induction is not coupled to the IL-2 receptor
Ehrlich et al., Cytokine 2003 : In particular, not only PHA+IL-2 but also LPS were able to induce secretion of soluble TRAIL, but did not enhance the expression of surface bound TRAIL
Ishiyama et al., Hepatology 2006 (Carcinoma, Hepatocellular...) : Stimulation with interleukin (IL)-2 , significantly up-regulated the expression of TRAIL on liver NK cells, but this effect was barely observed on PB NK cells
Naoe et al., Oncol Res 2011 (Carcinoma, Renal Cell...) : The upregulation of TNF related apoptosis inducing ligand on NK cell by IL-2 and suppression of regulatory T cells ( Tregs ) by IFN-alpha were recognized at the same time when cytotoxicity of peripheral blood mononuclear cells ( PBMCs ) was enhanced