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IL2 — TXN
Text-mined interactions from Literome
Koura et al., Thorax 2000
(Granuloma, Respiratory Tract...) :
The expression of TRX and IL-2R in granulomas of patients with sarcoidosis has been studied to clarify a possible
role for
TRX in the induction of
IL-2R expression
Pekkari et al., Blood 2001
:
Truncated
thioredoxin ( Trx80 )
induces production of
interleukin-12 and enhances CD14 expression in human monocytes ...
Trx80 alone induced secretion of IL-12 from CD40 ( + ) monocytes in the PBMC cultures and this effect was
enhanced by
IL-2
Fujiwara et al., Jpn J Pharmacol 1990
:
In addition,
SASP and CsA
inhibited the production of
interleukin 2 (IL-2) from splenocytes in these experiments
Asami et al., PloS one 2013
:
TRX significantly
suppressed the serum levels of
interleukin-1ß ( p < 0.05 ), although neither anti-apoptotic nor anti-chemotactic effects were observed
Tagaya et al., Immunol Lett 1987
(Deltaretrovirus Infections) :
Transcription of
IL-2 receptor gene is
stimulated by
ATL derived factor produced by HTLV-I ( + ) T cell lines ...
ADF enhances the expression of the
IL-2-R through the augmentation of the IL-2-R mRNA in the HTLV-I ( + ) T-cell line ( ED ) as well as the NK cell line cells ( YT )
Furuke et al., Int Immunol 1995
:
In addition, exogenous
IL-2 could not
increase ADF/TRX production in FK506 treated PBMC or in PHA blasts ... These results indicate that ADF/TRX induction in T cell activation depends on calcineurin dependent events in the early phase and that
IL-2 production is not directly
involved in
ADF/TRX induction
Söderberg et al., Scand J Immunol 1997
(Leukemia, Lymphocytic, Chronic, B-Cell) :
In clear contrast,
SAC+IL-2+ Trx induced DNA synthesis of normal B cells was not inhibited by soluble anti-CD40 MoAb