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IKBKB — SGK1

Text-mined interactions from Literome

Zhang et al., Cancer Res 2005 (Breast Neoplasms) : We also show that SGK enhances the ability of IKKbeta to phosphorylate endogenous IkappaBalpha in cells or recombinant glutathione S-transferase-IkappaBalpha in vitro and increases IkappaBalpha degradation ; SGK physically associates with and activates IKKbeta in MDA231 cells via phosphorylation of Ser ( 181 ) in IKKbeta
Tai et al., J Biol Chem 2009 : Although SGK1 does not phosphorylate IKKbeta, IKKbeta activity is still required for IKK complex activation and for SGK1 phosphorylation and activation of NF-kappaB