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ACE — NPPA
Text-mined interactions from Literome
Nyström et al., Scand J Clin Lab Invest 1998
:
ACE correlated negatively with cGMP in men ( all ; r = -0.22, p = 0.03, 45-69 years of age r = -0.49, p = 0.0002 ) and this correlation was
independent of
ANP , ACE, ABP and age
Hu et al., Basic Res Cardiol 2001
(Myocardial Infarction) :
The
effects of
angiotensin converting enzyme (ACE) inhibition ( quinapril, 6 mg/kg/day ) and angiotensin II type 1 (AT1) receptor blockade ( losartan, 10 mg/kg/day ) on
ANP levels in 18 selected, microdissected brain nuclei were determined in sham operated rats and rats with left ventricular dysfunction 8 weeks after myocardial infarction ( MI )
Heintz et al., Clin Physiol Biochem 1992
(Heart Failure) :
Conclusion :
ACE inhibition does not
induce changes in
ANP or ADH levels in the resting state while Ang II decreases
Cockcroft et al., J Hum Hypertens 1989
:
This has been investigated within the forearm vascular bed during local
ANP infusion and
ACE inhibition
Saijonmaa et al., Cardiovasc Res 1998
:
To examine the
role of
atrial natriuretic peptide (ANP) and cyclic GMP in the regulation of
angiotensin converting enzyme (ACE) in cultured human endothelial cells ...
ANP caused a dose dependent increase in
ACE measured in intact endothelial cell culture ... These data suggest that cGMP is an intracellular mediator regulating ACE and that
ANP induced increase of
ACE is mediated via a cGMP dependent mechanism