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CD79A — IKBKB
Text-mined interactions from Literome
Patke et al., Curr Opin Immunol 2004
:
BCR signaling
leads to activation of the
inhibitor of NF-kappa B kinase (IKK) complex via Carma1, Bcl10 and MALT1, whereas BAFF-R engagement promotes processing of NF-kappa B2 protein p100, which is dependent on NF-kappa B-inducing kinase (NIK) and IKK alpha
Francés et al., J Immunol 2005
(Calcium Signaling) :
The same B-1 cells manifested defective
BCR mediated
induction of
IKKbeta phosphorylation, IkappaBalpha degradation, and intracellular Ca ( 2+ ) mobilization
Shinohara et al., J Exp Med 2007
:
We show that PKCbeta mediates phosphorylation of CARMA1 on Ser668, which in turn is essential for
BCR mediated CARMA1-Bcl10-mucosal associated lymphoid tissue 1 ( MALT1 ) association and subsequent
IKK activation
Kometani et al., J Exp Med 2011
:
These mice had impaired T cell independent type II antibody responses in vivo and diminished
IKK-ß activation and cellular
responses to
B cell receptor (BCR) cross linking in vitro