Gene interactions and pathways from curated databases and text-mining

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MAP3K8 — TLR9

Text-mined interactions from Literome

Sugimoto et al., J Clin Invest 2004 : We show here that Cot/Tpl2 is also activated by other Toll-like receptor ( TLR ) ligands
Kaiser et al., J Exp Med 2009 : However, in the absence of TPL-2 signaling, lipopolysaccharide ( TLR4 ) and CpG ( TLR9 ) stimulation resulted in increased production of IFN-beta while decreasing IL-10 production by both macrophages and myeloid DCs