Gene interactions and pathways from curated databases and text-mining

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CD8A — CXCR3

Text-mined interactions from Literome

Mohan et al., Eur J Immunol 2005 (Dermatitis...) : Blocking CXCR3 inhibited recruitment of 60-85 % of unstimulated T cells and up to 90 % of CD8 ( + ) CD45RC ( + ) effector T cells, but caused < 50 % inhibition of CD4 ( + ) and CD8 ( + ) memory ( CD45RC ( - ) ) T cells
Jiang et al., Transpl Immunol 2010 : To date, the effect of CXCL16 ( SR-PSOX ) /CXCR6 on CD8 ( + ) T cells and its role in allograft rejection/acceptance are not well understood
Kurachi et al., J Exp Med 2011 : We demonstrate that the chemokine receptor CXCR3 is involved in promoting CD8 ( + ) T cell commitment to an effector fate rather than a memory fate by regulating T cell recruitment to an antigen/inflammation site