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CD8A — CXCR3
Text-mined interactions from Literome
Mohan et al., Eur J Immunol 2005
(Dermatitis...) :
Blocking
CXCR3 inhibited recruitment of 60-85 % of unstimulated T cells and up to 90 % of CD8 ( + ) CD45RC ( + ) effector T cells, but
caused < 50 % inhibition of CD4 ( + ) and
CD8 ( + ) memory ( CD45RC ( - ) ) T cells
Jiang et al., Transpl Immunol 2010
:
To date, the
effect of CXCL16 ( SR-PSOX )
/CXCR6 on
CD8 ( + ) T cells and its role in allograft rejection/acceptance are not well understood
Kurachi et al., J Exp Med 2011
:
We demonstrate that the chemokine receptor
CXCR3 is
involved in promoting
CD8 ( + ) T cell commitment to an effector fate rather than a memory fate by regulating T cell recruitment to an antigen/inflammation site