Gene interactions and pathways from curated databases and text-mining

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AXIN2 — E2F1

Text-mined interactions from Literome

Hughes et al., Exp Cell Res 2005 : Cross-talk between pRb/E2F and Wnt/beta-catenin pathways : E2F1 induces axin2 leading to repression of Wnt signalling and to increased cell death ... Cross-talk between pRb/E2F and Wnt/beta-catenin pathways : E2F1 induces axin2 leading to repression of Wnt signalling and to increased cell death
Hughes et al., Biochem Biophys Res Commun 2005 : Axin2 is induced by E2F1 and therefore acts as a point of cross-talk between the pRb/E2F and Wnt/beta-catenin pathways : two of the most frequently deregulated pathways in human cancers