UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to TNF

CFB — TNF

Pathways - manually collected, often from reviews:

OpenBEL Selventa BEL large corpus: CFB → TNF (increases)
Evidence: TNF increased synthesis of factor B by 18.6-fold; IL-4 reduced the TNF effect on factor B synthesis by 83%.
OpenBEL Selventa BEL large corpus: CFB → TNF (increases, TNF Translocation) Andoh et al., Clin Exp Immunol 1999 *
Evidence: sodium butyrate enhanced TNF-alpha-induced C3 secretion, but suppressed TNF-alpha-induced factor B and IL-8 secretion.

Text-mined interactions from Literome

Chen et al., Exp Eye Res 2008 : Confocal microscopy and real-time PCR of RPE cultures indicated that the production of CFB by RPE cells is positively regulated by TNF-alpha , IFN-gamma and long-term ( 30 days ) photoreceptor outer segments treatments
Singh et al., J Mol Cell Cardiol 2012 (Cardiomegaly...) : In contrast, TNF-a induced Cfb gene expression was not deficient in MyD88 ( -/- ) cardiomyocytes