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AXIN1 — MAP3K1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: MAP3K1 — AXIN1 (physical association, affinity chromatography technology) Sue Ng et al., Biol Chem 2010
• IRef Biogrid Interaction: MAP3K1 — AXIN1 (physical association, affinity chromatography technology) Zhang et al., J Biol Chem 2002*
• IRef Biogrid Interaction: MAP3K1 — AXIN1 (physical association, affinity chromatography technology) Zhang et al., J Biol Chem 2000*
• IRef Intact Interaction: Complex of 11 proteins (association, anti bait coimmunoprecipitation) Li et al., Cell 2012

Text-mined interactions from Literome

Kim et al., J Biol Chem 2003 : Overexpression of axin1 , a GSK3 beta regulated scaffolding protein, did not affect the physical interaction between GSK3 beta and MEKK1 in transfected HEK293 cells
Luo et al., J Biol Chem 2003 : Expression of specific small interfering RNA against MEKK4 effectively attenuates JNK activation by the MEKK1 binding-defective Axin mutant in 293T cells and inhibits JNK activation by wild-type Axin in MEKK1-/- cells, confirming that MEKK4 is indeed another mitogen activated protein kinase kinase kinase that is specifically involved in Axin mediated JNK activation independently of MEKK1