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Jeon et al., Toxicol Appl Pharmacol 2002
:
PCB 153 significantly increased caspase-3 activity in both spleen cells and human leukemia cells, and z-VAD-fmk, a general inhibitor of caspases, prevented PCB induced DNA fragmentation
Ptak et al., Toxicol Ind Health 2011
(Breast Neoplasms) :
From the PCB congeners tested, PCB138 and 153 had the highest stimulatory effects on basal cell proliferation as well as the highest inhibitory actions on basal caspase-9 activity