Gene interactions and pathways from curated databases and text-mining

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ERF — NGF

Text-mined interactions from Literome

Rao et al., Mol Cancer Ther 2010 (Leukemia, Myeloid, Acute) : Exposure to 17-DMAG inhibited NGF induced p-TrkA, p-AKT, and p-ERK1/2 levels, as well as induced apoptosis of K562, 32D cells with ectopic expression of wild-type TrkA or the constitutively active mutant Delta TrkA, and of primary myeloid leukemia cells
Chang et al., Biochim Biophys Acta 2013 : One mechanism that ES enhances neurite outgrowth is through increasing NGF induced phosphorylation of ERK1/2 ( pERK1/2 ) and expression of Egr1 gene ... Our result indicates that activating PKC further increases NGF induced pERK1/2 and thus neurite outgrowth