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MT3 — TP53

Text-mined interactions from Literome

Fan et al., Br J Cancer 2002 (Breast Neoplasms) : This study examines the effect of tumour suppressor protein p53 on metallothionein expression following CdCl2 treatment in eight human epithelial breast cancer cell lines differing in p53 and oestrogen-receptor status ... This effect may be associated with the occurrence of apoptosis and suggests a role for p53 and oestrogen-receptor on the expression and induction of metallothionein in epithelial cells
Liu et al., Toxicol Lett 2009 : The present study was to investigate whether Ang II induces p53 expression and activation and if so, whether Ang II-induced cardiac cell death is p53 dependent, and whether a potent antioxidant metallothionein ( MT ) prevents Ang II-induced p53 expression, and associate apoptotic cell death signaling
Formigari et al., J Appl Toxicol 2013 (Hepatolenticular Degeneration) : The protein p53 also plays a crucial role in the transcriptional regulation of metallothionein , which indicates a novel regulatory role for p53