Shukla et al., Nat Cell Biol 2009
:
Here we show that transforming growth factor beta ( TGF-beta ) promotes the expression of CLIC4 and Schnurri-2 as well as their association in the cytoplasm and their translocation to the nucleus
Yao et al., Molecular cancer 2009
(Ovarian Neoplasms) :
These results convincingly show that ROS and CLIC4 are responsible for TGF-beta1 induced fibroblast-to-myofibroblast transdifferentiaton and down-regulation of both is sufficient to block transdifferentiated myofibroblasts