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F2RL1 — MIP
Text-mined interactions from Literome
Lee et al., Am J Physiol Lung Cell Mol Physiol 2005
(Inflammation...) :
Dexamethasone inhibited the
PAR(2) mediated
MIP-2 release in a dose dependent manner
Su et al., J Immunol 2005
(Acute Disease...) :
In bronchoalveolar lavage,
PAR2 activation
caused 8- and 5-fold increase in
MIP-2 and substance P levels, respectively, and a 12-fold increase in the number of neutrophils
Peters et al., J Pharmacol Exp Ther 2010
(Disease Models, Animal...) :
However, neither PAR(2) activating peptides nor PGE ( 2 ) inhibited LPS induced generation of
MIP-2 in cultures of primary murine alveolar macrophages In summary,
PAR(2) activating peptides and PGE ( 2 ) suppressed LPS induced neutrophilia in murine airways, independently of an inhibitory action on MIP-2 generation by alveolar macrophages