Gene interactions and pathways from curated databases and text-mining

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F2RL1 — MIP

Text-mined interactions from Literome

Lee et al., Am J Physiol Lung Cell Mol Physiol 2005 (Inflammation...) : Dexamethasone inhibited the PAR(2) mediated MIP-2 release in a dose dependent manner
Su et al., J Immunol 2005 (Acute Disease...) : In bronchoalveolar lavage, PAR2 activation caused 8- and 5-fold increase in MIP-2 and substance P levels, respectively, and a 12-fold increase in the number of neutrophils
Peters et al., J Pharmacol Exp Ther 2010 (Disease Models, Animal...) : However, neither PAR(2) activating peptides nor PGE ( 2 ) inhibited LPS induced generation of MIP-2 in cultures of primary murine alveolar macrophages In summary, PAR(2) activating peptides and PGE ( 2 ) suppressed LPS induced neutrophilia in murine airways, independently of an inhibitory action on MIP-2 generation by alveolar macrophages