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EGF — GCG
Text-mined interactions from Literome
de Juan et al., Exp Cell Res 1992
:
Glucagon or norepinephrine did not affect EGF stimulation of DNA synthesis in fetal liver cells, but they
potentiated EGF response in regenerating hepatocyte cultures
Peinado-Onsurbe et al., Biochim Biophys Acta 1992
(Starvation) :
( ii ) In isolated hepatocytes, secretion of lipoprotein lipase activity was increased by adrenaline, dexamethasone and
glucagon but was not
affected by
epidermal growth factor , insulin or triiodothyronine
Jansen et al., Eur Surg Res 2006
:
Our data suggest that
EGF might
play an important role in the regulation of
glucagon secretion by preventing the lowering effect of glucose on plasma glucagon levels
Baribault et al., J Cell Physiol 1985
:
For suckling rat hepatocytes
EGF was required, but its stimulating action was
dependent on insulin and/or
glucagon
Marigo et al., Dev Biol Stand 1985
:
These results disclose the existence of two quite different mechanisms by which neonatal rat hepatocyte growth can be stimulated : ( i ) the physiological-pharmacological extracellular calcium dependent SOD-insensitive machinery,
mediating the effects of
EGF ,
glucagon , insulin, imidazole, and indomethacin ; and ( ii ) the pathological extracellular calcium independent SOD-suppressible mechanism operated by agents belonging to the tumor promoters class and involving, as a critical step, the generation of superoxide anions at the surface of the hepatocyte 's plasma membrane
Ulrich et al., Cell Biochem Funct 1998
:
Activation and
glucagon regulation of mitogen activated protein kinases ( MAPK ) by insulin and
epidermal growth factor in cultured rat and human hepatocytes ...
Glucagon also
reduced the activation of MAPK by
EGF in rat hepatocytes