◀ Back to EGF

EGF — NOX1

Text-mined interactions from Literome

Frank et al., Endocrinology 2000 : In the presence of a NADH/NADPH oxidase inhibitor, diphenyleneiodonium ( DPI ) or an antioxidant, alpha-tocopherol, Ang II-induced protein tyrosine phosphorylation of two major proteins ( p120, p70 ) and ERK activation were markedly reduced, whereas ERK activation by epidermal growth factor was unaffected
Carmona-Cuenca et al., J Cell Physiol 2006 : EGF blocks NADPH oxidase activation by TGF-beta in fetal rat hepatocytes, impairing oxidative stress, and cell death
Schreiner et al., Cardiovasc Res 2011 : Experiments using the blocking peptide gp91ds-tat verified a role for Nox1 in Ang II signalling towards Akt, but excluded a role for Nox1 in the respective EGF signalling
Flinder et al., J Cell Physiol 2011 : EGF induced ERK-activation downstream of FAK requires rac1-NADPH oxidase