Gene interactions and pathways from curated databases and text-mining

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AQP8 — IRF6

Text-mined interactions from Literome

Lehmann et al., Am J Physiol Gastrointest Liver Physiol 2008 (Cholestasis...) : LPS induces the TNF-alpha mediated downregulation of rat liver aquaporin-8 : role in sepsis associated cholestasis ... In conclusion, our data suggest that LPS induces the TNF-alpha mediated posttranscriptional downregulation of AQP8 functional expression in hepatocytes, a mechanism potentially relevant to the molecular pathogenesis of sepsis associated cholestasis
Shen et al., Respirology 2012 : The aim of this study was to investigate the changes in expression of aquaporins ( AQP ) during differentiation of human bronchial epithelial cells and the role of lipopolysaccharide (LPS) in AQP expression ... Western blotting was performed to assess the effects of LPS on AQP3, AQP4 and AQP5 expressions in normal human bronchial epithelial cells