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Text-mined interactions from Literome
Lei et al., Infect Immun 2000
:
In RAW264.7 cells, both
caveolin-1 mRNA and protein levels are
down-regulated by
LPS ... In TG-elicited C3HeB/FeJ peritoneal macrophages, in contrast, expression of both
caveolin-1 protein and mRNA is up-regulated in vitro in
response to
LPS stimulation
Walton et al., Arterioscler Thromb Vasc Biol 2003
:
Supporting an important role for caveolae in LPS action, overexpression of
caveolin-1 enhanced
LPS induced IL-8 synthesis
Lei et al., Infect Immun 2005
:
Interestingly, polymyxin B ( 5 microg/ml ) and RsDPLA show only a limited capacity to inhibit
LPS induced
caveolin-1 expression ... These findings suggest that expression of
caveolin-1 in
response to
LPS may only partially be dependent upon lipid A. Recombinant tumor necrosis factor alpha marginally induces caveolin-1, suggesting that the ability of LPS to regulate caveolin-1 is not mediated primarily through an autocrine/paracrine mechanism involving this cytokine ... Gamma interferon treatment inhibits the
induction of
caveolin-1 by
LPS in macrophages