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IRF6 — TNFRSF11B

Text-mined interactions from Literome

Li et al., Zhonghua Kou Qiang Yi Xue Za Zhi 2003 : To investigate the effects of LPS and/or TNF-alpha on periodontal ligament cell ( PDLC ) proliferation and OPG secretion
Suda et al., J Immunol 2004 : LPS induced both stimulation of RANKL mRNA expression and inhibition of OPG mRNA expression in osteoblasts ... NS398 blocked LPS induced down-regulation of OPG mRNA expression, but not LPS induced up-regulation of RANKL mRNA expression, suggesting that down-regulation of OPG expression by PGE ( 2 ) is involved in LPS induced osteoclast formation in the cocultures
Wada et al., Bone 2004 : The present study examined the effects of Escherichia coli LPS on the gene expression of interleukin-1 beta (IL-1 beta), tumor necrosis factor-alpha (TNF-alpha), OPG , and receptor activator of NF-kappa B ligand ( RANKL ) in HPLF using semiquantitative reverse transcription-polymerase chain reaction ( RT-PCR ) analysis ... These suggest that LPS stimulates both OPG and RANKL expression in HPLF by up-regulating IL-1 beta and TNF-alpha
Tiranathanagul et al., J Periodontol 2004 (Alveolar Bone Loss) : The upregulation of RANKL but not OPG by the LPS was found in both transcription and translation and could be reduced by indomethacin
Tanaka et al., Life Sci 2006 : The present study was undertaken to determine the effect of nicotine and LPS on the expression of macrophage colony stimulating factor ( M-CSF ), osteoprotegerin (OPG) , and prostaglandin E2 ( PGE2 ) in osteoblasts, and the indirect effect of nicotine and LPS on the formation of osteoclast-like cells
Coon et al., J Endod 2007 (Bone Resorption...) : LPS and endodontic materials caused a decrease in both RANKL and OPG expression in WT cells
Kiji et al., Clin Exp Immunol 2007 (Chronic Disease...) : Both A. actinomycetemcomitans and P. gingivalis LPS augmented OPG expression in HGF ... These results suggest that LPS induced OPG production by HGF is regulated via EP1 and/or EP2 receptors by endogenously generated PGE ( 2 )
Nakamura et al., Oral Microbiol Immunol 2008 (Alveolar Bone Loss...) : Few in vivo studies have demonstrated whether Toll-like receptor 4 (TLR4) is indispensable for lipopolysaccharide (LPS) induced bone resorption and little is known about the receptor activator of nuclear factor-kappaB ligand ( RANKL ) and osteoprotegerin (OPG) expression induced by LPS under conditions of lack of TLR4
Jang et al., Phytother Res 2010 (Bone Resorption) : NS-398 inhibited the effect of LPS on RANKL and OPG expression in osteoblasts
Byron et al., Am J Vet Res 2010 : Soluble OPG release into media was significantly increased by hrIL-1beta and LPS in chondrocyte but not in synoviocyte cultures ... The soluble OPG : RANKL ratio was significantly increased by LPS in chondrocyte cultures