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BMP15 — SOST

Text-mined interactions from Literome

Kusu et al., J Biol Chem 2003 : We examined effects of sclerostin on the activity of BMP2, BMP4, BMP6 , and BMP7 for mouse preosteoblastic MC3T3-E1 cells
Ohyama et al., Endocrinology 2004 : Spaciotemporal association and bone morphogenetic protein regulation of sclerostin and osterix expression during embryonic osteogenesis
van Bezooijen et al., J Bone Miner Res 2007 : Transcriptional profiling analysis of osteoblastic cultures indicated that sclerostin specifically affects BMP and Wnt signaling out of many other growth signaling pathways ... Sclerostin , however, did not inhibit stimulation of direct BMP target genes ... Sclerostin inhibits BMP stimulated bone formation but does not affect BMP signaling
Delgado-Calle et al., J Bone Miner Res 2012 : In addition, BMP-2 induced expression of SOST was markedly enhanced in cells demethylated by AzadC
Qin et al., Yi Chuan 2013 : SOST can regulate osteoblastic differentiation and bone formation by binding type I/II receptors and co-receptor LRP5/6 to inhibit BMP and Wnt signaling pathways