Gene interactions and pathways from curated databases and text-mining

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FOS — MMP7

Text-mined interactions from Literome

Westermarck et al., FASEB J 1999 (Neoplasm Invasiveness...) : This review will summarize the current view on the role of MMPs in tumor growth, invasion, and survival, and focus on the role of mitogen activated protein kinases and AP-1 and ETS transcription factors in the regulation of MMP gene expression during invasion process
Kajanne et al., J Cell Physiol 2007 : Here we provide genetic and biochemical evidence that EGF-R- and AP-1 mediated signals are required for MMP expression and collagen contraction in fibroblasts
Oliver et al., J Rheumatol 2007 (Arthritis, Experimental...) : We evaluated whether a vanadium AP-1 inhibitor could reduce MMP expression and subsequent joint damage in CIA
Kim et al., Biosci Biotechnol Biochem 2007 (Colorectal Neoplasms) : Although CUR abolished the EGCG upregulated MMP-7 mRNA expression, it unexpectedly enhanced the AP-1 activity by 502 %, suggesting that this factor may disrupt the MMP-7 mRNA stabilization process
Yuan et al., Mol Cell Biochem 2008 : Our data suggest that HRG-beta induced MMP-7 expression was regulated by HER2 mediated AP-1 activation in MCF-7 cells
Hasegawa et al., Exp Cell Res 2009 (Neoplasm Invasiveness) : To assess the role of AP-1 function, we examined the effects of dominant negative Fos ( DeltaFos ), BATF and siRNA against c-Jun on MMP production in v-Crk transformed cells which have augmented production of MMP-2 and MMP-9
Ho et al., International journal of biological sciences 2011 (Adenocarcinoma...) : Moreover, H2O2 triggered MMP-7 production was demonstrated via JNK/c-Jun and ERK/c-Fos activation in an activating protein 1 (AP-1) dependent manner ... Taken together, these results suggest that DMA suppresses H2O2 induced cell invasion by inhibiting AP-1 mediated MMP-7 gene transcription via the JNK/c-Jun and ERK/c-Fos signaling pathways in SW620 human colon cancer cells
Jia et al., Int J Colorectal Dis 2012 (Colonic Neoplasms...) : Tissue factor/activated factor VIIa induces matrix metalloproteinase-7 expression through activation of c-Fos via ERK1/2 and p38 MAPK signaling pathways in human colon cancer cell