Gene interactions and pathways from curated databases and text-mining

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NBN — RPA2

Text-mined interactions from Literome

Jurvansuu et al., J Virol 2005 : In cells, such DNA accumulates into nuclear foci with a signaling apparatus that involves DNA polymerase delta, ATR, TopBP1, RPA , and the Rad9/Rad1/Hus1 complex but not ATM or NBS1
Manthey et al., J Cell Sci 2007 (Cell Transformation, Viral) : Here, we report that hydroxyurea ( HU ) -induced RPA phosphorylation requires both NBS1 ( NBN ) and NBS1 phosphorylation
Oakley et al., Biochemistry 2009 : Thus, the N-terminus of RPA1 and phosphorylation of RPA2 regulate RPA-MRN interactions and are important in the response to DNA damage
Shiotani et al., Cell reports 2013 : Importantly, the role of Nbs1 in RPA32 phosphorylation can be separated from ATM activation and DSB resection, and it is dependent upon the interaction of Nbs1 with RPA