◀ Back to PPARGC1A
MAPK12 — PPARGC1A
Pathways - manually collected, often from reviews:
-
Reactome Reaction:
MAPK12
→
PPARGC1A
(reaction)
Blanco-Aparicio et al., J Cell Biol 1999*, Knutti et al., Proc Natl Acad Sci U S A 2001*, Wright et al., J Biol Chem 2007*, Gibala et al., J Appl Physiol 2009*, Little et al., Am J Physiol Regul Integr Comp Physiol 2011*, Jiang et al., J Biol Chem 1997*
Text-mined interactions from Literome
Rasbach et al., J Biol Chem 2007
(Reperfusion Injury) :
Additional inhibitor studies revealed that the sequential activation of Src, p38 MAPK, EGFR, and p38
MAPK regulate the expression of
PGC-1alpha following oxidant injury
Luo et al., J Mol Neurosci 2009
(Reperfusion Injury) :
At the same time, PD98059 ( ERK MAPK inhibitor ) and SB203580 ( P38 MAPK inhibitor ) also prevented the up-regulation of
PGC-1alpha in OGD neurons and MK801 can
inhibit the expression of P38 and ERK
MAPK