◀ Back to PTPN11

CTNND1 — PTPN11

Text-mined interactions from Literome

Hakak et al., Mol Cell Biol 1999 (MAP Kinase Signaling System) : Coexpression of Cas with v-Src enhanced the association of Grb2 with the adapter protein Shc and the protein tyrosine phosphatase Shp-2 ; coexpression of Shc or Shp-2 mutants significantly reduced SRE activation by Cas and v-Src ... Cas induced Grb2 association with Shp-2 and Shc may account for the Cas dependent activation of the Ras/Mek/Erk pathway and SRE dependent transcription
Inagaki et al., Oncogene 2000 : Inhibition of SHP-2 also markedly increased the rate of cell attachment to and cell spreading on extracellular matrix proteins such as fibronectin and vitronectin, effects that were accompanied by enhancement of adhesion induced tyrosine phosphorylation of paxillin and p130Cas