◀ Back to IL12B
HLA-DRA — IL12B
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Toyokawa et al., Anticancer Res 2002
:
Both OK432 and KP-40 were found to up-regulate the activity of myeloid-lineage DCs : the expression of major histocompatibility complex (
MHC) class II molecules and adhesion/costimulatory molecules
increased , and the production of
IL-12 also increased
Kawanokuchi et al., Mult Scler 2006
:
Stimulation of microglia with
IL-12 and IL-18
resulted in
MHC class II mRNA expression in microglia
Marshall et al., J Immunol 2008
(MAP Kinase Signaling System) :
During this process, cells initiate proteolytic degradation of internalized protein Ags into peptides that complex with
MHC class II (MHC II) and simultaneously
increase expression of costimulatory molecules and of cytokines such as IL-6, IL-12, and
IL-23 ... During this process, cells initiate proteolytic degradation of internalized protein Ags into peptides that complex with
MHC class II (MHC II) and simultaneously
increase expression of costimulatory molecules and of cytokines such as IL-6,
IL-12 , and IL-23
Suemoto et al., J Dermatol Sci 1998
:
The expression of
MHC class II , CD80 and CD86 on EC was not
affected by
IL-12