Gene interactions and pathways from curated databases and text-mining

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STX4 — STXBP1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Toonen et al., J Neurochem 2005 (Synaptic Transmission) : Munc18-1 stabilizes syntaxin 1, but is not essential for syntaxin 1 targeting and SNARE complex formation ... Pulse-chase analysis in transfected HEK293 cells revealed that Munc18-1 directly promotes the stability of syntaxin 1, consistent with a chaperone function
Arunachalam et al., Mol Biol Cell 2008 : Munc18-1 is critical for plasma membrane localization of syntaxin1 but not of SNAP-25 in PC12 cells ... Here we investigated the role of Munc18-1 in syntaxin1 localization by generating stable neuroendocrine cell lines in which Munc18-1 was strongly down-regulated
Oh et al., J Biol Chem 2012 : Pre docked syntaxin 1-based SNARE complexes bound by Munc18-1 were detected in ß-cell lysates but, surprisingly, were reduced by elevation of Munc18-1 levels
Pevsner et al., Neuron 1994 : Recombinant n-sec1 inhibited VAMP or SNAP-25 binding to syntaxin