Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Dorward et al., J Leukoc Biol 2013 : Neutrophil activation was measured in unstimulated unsorted and sorted cells and in response to fMLF, LTB4, and PAF by measuring shape change, CD62L , and CD11b expression ; intracellular calcium flux ; and chemotaxis
Berends et al., Eur Respir J 1997 : Concentration dependent inhibition of the PAF induced CD11b expression and L-selectin shedding for neutrophils and eosinophils was observed with rolipram, dibutyryl cyclic adenosine monophosphate ( cAMP ), prostaglandin E2 ( PGE2 ), and isoproterenol
Knight et al., J Leukoc Biol 1997 : PAF up-regulated the expression of CDllb/CD18, down-regulated L-selectin , and also increased F-actin assembly in eosinophils
Tsang et al., J Immunol 1997 (Second Messenger Systems) : Stimulation through L-selectin induced membrane ruffling, whereas PAF or IL-8 induced bipolar shape change