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FGF1 — STAT1

Text-mined interactions from Literome

Sahni et al., Genes Dev 1999 : FGF treatment of RCS cells induces phosphorylation of STAT-1 , its translocation to the nucleus, and an increase in the expression of the cell-cycle inhibitor p21WAF1/CIP1
Zhang et al., Exp Eye Res 2005 : Retinas from embryonic and neonatal stages showed that STAT3 but not STAT1 was activated in response to ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), fibroblast growth factor-1 (FGF1) , fibroblast growth factor-2 (FGF2), epidermal growth factor (EGF), interferon-alpha ( IFN-alpha ) and interferon-gamma (IFN-gamma) in distinct patterns
Krejci et al., J Cell Sci 2008 : However, as demonstrated by western blotting with phosphorylation-specific antibodies, imaging of STAT nuclear translocation, STAT transcription factor assays and STAT luciferase reporter assays, FGF does not activate STAT1 or STAT3 in RCS chondrocytes, which nevertheless respond to a FGF stimulus with potent growth arrest
Krejci et al., Cell Signal 2009 : Despite the accumulation, both endogenous and cytokine induced activation of STAT1 and STAT3 is impaired by FGF , as demonstrated by imaging of active STAT nuclear translocation and analyses of STAT activatory phosphorylation and transcriptional activation
Johnson et al., Oncogene 1998 (Breast Neoplasms...) : FGF signaling activates STAT1 and p21 and inhibits the estrogen response and proliferation of MCF-7 cells