Gene interactions and pathways from curated databases and text-mining

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ITGB1 — TGFBR1

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: Complex of ITGA3-ITGB1 → TGFBR1 (increases, ITGA3/ITGB1 Activity)
    Evidence: TGF-B is a potent regulator of cellular adhesion, motility, and the extracellular matrix. TGF-B regulates the adhesive properties of cells by decreasing the expression of E-cadherin59 to decrease cell adhesion, by increasing the expression of invasion-associated integrins including AIIIB1 integrin, and by increasing the expression of integrin-binding proteins including fibulin