Gene interactions and pathways from curated databases and text-mining

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ANG — DUSP1

Text-mined interactions from Literome

Hiroi et al., Hypertens Res 2001 : Ang II increased MAPK phosphatase 1 (MKP-1) gene expressions within 10 min. Levels of MKP-1 transcripts peaked at 30 min and gradually decreased thereafter
McCollum et al., Am J Physiol Heart Circ Physiol 2012 (Cardiomegaly...) : However, ANG- ( 1-7 ) infusion, with or without ANG II, increased the MAPK phosphatase dual-specificity phosphatase (DUSP)-1 ; in contrast, treatment with ANG II had no effect on DUSP-1, suggesting that ANG- ( 1-7 ) upregulates DUSP-1 to reduce ANG II-stimulated ERK activation
McCollum et al., Peptides 2012 (Fibrosis...) : In contrast, Ang- ( 1-7 ) increased dual-specificity phosphatase DUSP1 immunoreactivity and mRNA, suggesting that the heptapeptide hormone increases DUSP1 to reduce MAP kinase phosphorylation and activity
Fischer et al., Am J Physiol 1998 : In contrast to the response in endothelial cells, however, ANG II activation of MKP-1 in ARVM was mediated by AT2-receptor activation