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ANG — DUSP1
Text-mined interactions from Literome
Hiroi et al., Hypertens Res 2001
:
Ang II
increased MAPK phosphatase 1 (MKP-1) gene expressions within 10 min. Levels of
MKP-1 transcripts peaked at 30 min and gradually decreased thereafter
McCollum et al., Am J Physiol Heart Circ Physiol 2012
(Cardiomegaly...) :
However, ANG- ( 1-7 ) infusion, with or without ANG II, increased the MAPK phosphatase dual-specificity phosphatase (DUSP)-1 ; in contrast, treatment with ANG II had no effect on DUSP-1, suggesting that
ANG- ( 1-7 )
upregulates DUSP-1 to reduce ANG II-stimulated ERK activation
McCollum et al., Peptides 2012
(Fibrosis...) :
In contrast,
Ang- ( 1-7 )
increased dual-specificity phosphatase DUSP1 immunoreactivity and mRNA, suggesting that the heptapeptide hormone increases DUSP1 to reduce MAP kinase phosphorylation and activity
Fischer et al., Am J Physiol 1998
:
In contrast to the response in endothelial cells, however,
ANG II
activation of
MKP-1 in ARVM was mediated by AT2-receptor activation