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CNTN2 — IL2

Text-mined interactions from Literome

Aqeilan et al., Biochem J 2003 : Indeed, a dramatic repression of nuclear Tax protein expression was induced following treatment of HUT-102 cells with IL-2-Bax , similar to what occurs following serum deprivation of these cells
Fung et al., Oncogene 2005 : Microarray analyses revealed several genes, including il-5, il-9 and il-13, are uniquely upregulated by IL-2 in the presence of Tax
Wano et al., Proc Natl Acad Sci U S A 1988 : Tax induction of the interleukin 2 gene is synergistically amplified by mitogens that augment cytoplasmic levels of calcium
Lanoix et al., Oncogene 1994 (Cell Transformation, Viral) : The Tax protein of HTLV-I, a positive transcriptional activator of HTLV-I gene expression, is a viral oncogene that also increases transcription of cellular genes including GM-CSF, IL-2R alpha and IL-2
Seeler et al., Virology 1993 : Tax activation of the IL-2 receptor and the HIV-1 LTR is mediated through NF-kappa B motifs
Good et al., EMBO J 1996 : In the present study, we demonstrate that neither NF-kappa B/Rel nor CREB/ATF is sufficient for Tax mediated activation of the IL-2 promoter ... Transient transfection studies demonstrate that the in vivo expressed NF-ATp binds to the CD28RE probe and enhances Tax mediated activation of this critical IL-2 enhancer ... Together, these results suggest a novel mechanism of Tax mediated activation of the IL-2 gene, which involves the induction of NF-AT containing CD28RE binding complexes
Papiez et al., Postepy Hig Med Dosw 1995 (Leukemia, T-Cell) : Tax increases the expression of cell protooncogenes as well as lymphokines, among others IL-2 and its receptor