Gene interactions and pathways from curated databases and text-mining

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IL2 — PTH

Text-mined interactions from Literome

Li et al., Biochem Biophys Res Commun 1991 : Effect of parathyroid hormone on release of interleukin 1 and interleukin 6 from cultured mouse osteoblastic cells
Smith et al., J Clin Lab Immunol 1990 : We have proceeded to compare the effects of the calciotrophic hormones, 1,25 ( OH ) 2D3, 24,25 dihydroxyvitamin D3 ( 24,25 ( OH ) 2D3 ), 25 dihydroxyvitamin D3 ( 25 ( OH ) D3 ), bovine ( 1-35 ) PTH ( b ( 1-35 ) PTH ) and salmon CT on both lymphocyte transformation and IL-2 activity in PBMC 's from normal human volunteers
Klinger et al., Kidney Int 1990 : PTH augmented IL-2 production by PHA activated T cells but did not increase expression of IL-2R
Angelini et al., Clin Nephrol 1994 (Hyperparathyroidism, Secondary...) : The elevated levels of PTH affect the lymphocyte function and are associated with change in cellular immunity with reduction in total number of T cells, and increases in levels of CD8, S-CD8 and IL-2R